Ten years later after completion of the Sher-Dor madrasah, Yalangtush Bahadur launched a new construction of a combination of a madrasah and juma-mosque, which was subsequently named Tillya-Kari (1646-1660). This building completed the composite design of the Registan.

The architecture of the facade of the Tillya-Kari is perceived as a worthy background for the two madrasahs located opposite each other. The madrasah is not placed on the main axis, but instead is located on the western side of the closed courtyard with the one-storey hujras. The wide courtyard with four ayvans is surrounded with cells. The western part of the structure is a domed mosque with two adjoining galleries on the posts, while the centre of the composition is a square cruciform room.
The interior of the mosque is decorated in the “kundal" style famous for its abundantly gilded ornamentation and background. In addition, the mihrab (the prayer niche showing the direction of Mecca) and minbar (a tribune for a preacher-imam) of the mosque were also gilded. The concentric relief paintings and gilt of the central hall were used to amaze visitors with its luxury and richness. This lavish gilt decoration gave the name to the madrasah- Tillya-Kari- which means “gold-covered”.
The outer and inner facades are faced with a brick mosaic and majolica with geometric, vegetative and epigraphical patterns. The massive wooden doors are decorated with a vegetative and epigraphical ornament.